Methods for Drug Delivery to the Brain discussed at PU

Chandigarh:

 Prof. V. R. Sinha, University Institute of Pharmaceutical Sciences, Panjab University highlighted the methods used for drug delivery to the brain and also emphasized on the advantages of parenteral route for drug delivery. Prof. Sinha discussed about the different types of nanoparticles which can be used for therapeutics. Furthermore, he talked about implants that can be used for contraceptive purposes. Prof. Sinha was addressing the participants on the third day of the International Brain Research Organization (IBRO) -Asia Pacific Regional Committee (APRC) supported seminar on the theme ‘Blood-Brain-Barrier: From Basic Physiology to Neurological Disorders’, here today

            Dr. Rakesh Pandey, CSIR-Central Institute of Medicinal and Aromatic Plants, Lucknow, highlighted the importance of model organisms in biomedical, environmental and plant sciences for easing research and development activities globally. His lab works on multicellular nematode Caenorhabditis elegans as a model to study the impact of various phytomolecules for their impact on ageing and age related neurodegenerative diseases.  C. elegans is one of the simplest
multicellular models on the earth, which unravels the most fundamental mysteries of modern science and can be easily cultured in large number in laboratory and they consume less finance and space. Although simple in handling, they reflect the complexity of human organ system specially the nervous system.

            The session followed an industrial talk given by Ankit Jain, technical manager, Merck Life Sciences Private Limited, where he featured some instruments for conducting research in neuroscience.

            Dr. Ravi Partap Banwal, Department of Biophysics, Panjab University, discussed the structural pathways of protein regulating blood brain barrier through highly efficient instrumentation. He also discussed about Neisseria meningitides, an infection that can lead to inflammation in the brain. Post lunch the participants went on a tour to Sophisticated Analytical Instrumentation Facility (SAIF)/ Central Instrumentation Lab (CIL)/UCIM, Panjab University for demonstration of
various instruments of the department.

            The day ended with experimental exposure to techniques to evaluate the functional aspects of blood brain barrier.

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